Memory Machine Cloud

Solutions

Delivers the world’s fastest & most efficient NGS solution

on Public Cloud

“ We have been impressed by the performance of the WaveRider for Sentieon solution. Early testing shows 4-5x speed-ups out-of-the-box and we expect to improve the results as we fine tune the solution. Faster processing coupled with leveraging spot instances is dramatically lowering our cloud cost too, This solution enables us to complete our NGS runs more efficiently than ever and will help elevate our research to a new level.”

– Remco Ursem, Program Leader of Bioinformatics, HZPC Research

Memory Machine™ Cloud

Sentieon License included in Memory Machine Cloud

Bioinformaticians’ Challenges

Running Next-Generation Sequencing (NGS) in the Cloud can be challenging:

  • NGS workloads, such as GATK, BWA-MEM, Picard require very long running time
  • Running long and resource-intensive workloads on the cloud is extremely costly
  • Managing Cloud is complex and has steep learning curve

MMCloud WaveRider for Sentieon Solution

  • ACCELERATES NGS workloads by 10x compared to Open Source software
  • REDUCES Cloud Cost by order of Magnitude
  • AUTOMATES deployment workloads in the Cloud

GATK / BWA are free
but not fast enough

Sentieon is fast
but expensive

Cloud is scalable
but costly

Optimizing resources
for NGS is difficult

MMCloud accelerates Sentieon on the Cloud

MMCloud dramatically reduces cloud cost for Sentieon

MMCloud includes Sentieon Licenses

MMCloud automatically optimizes resources for NGS workloads

MMCloud WaveRider for Sentieon solution provides drop-in replacement for GATK, BWA-MEM, STAR, Minimap2, Mutect2, and large cohort joint calling to do:

BAM Process
VCF Filtering
Long Reads
QC Statistics
RNA Variant Calling
Germline Variant Calling
Somatic Variant Calling

WaveRider for Sentieon solution is easy to use:

1

Deploy
Memory Machine Cloud

15~30 min

2

Choose Sentieon pipeline script or provide your own script

3

Launch Sentieon workload via Mmeory Machine Cloud

1 min

WaveRider for Sentieon Benchmark Results

Whole Genome Sequencing (WGS) Benchmark:

Baseline: Sentieon on AWS using On-demand instance
vs
WaveRider for Sentieon using On-demand instances

Benchmark Details

WaveRider for Sentieon – WaveWatcher Screenshots

Summary